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You wouldn’t know it by looking at any just one of us, but coursing via our veins each second of just about every working day are tiny variations that categorize our blood into groups: A+, A-, B+, B-, O-, O+, AB+ and AB-. 

These minute dissimilarities commonly don’t subject until finally they matter — when you are in the clinic in require of a blood transfusion, or right after you have donated blood, and you master which type you have. Some individuals locate out all through pregnancy, when particular treatment is necessary for an individual with a detrimental blood type.

But ongoing analysis into blood variety indicates it could issue far more than we believe it does — at least when examining possibility for sure overall health problems, specially coronary heart illness. These invisible distinctions in the blood may possibly give some men and women an edge at staving off cardiovascular issues, and could go away some others more prone.

What does blood kind necessarily mean, and how are they unique?

The letters A, B and O characterize several varieties of the ABO gene, which system our blood cells otherwise to form the distinct blood groups. If you have sort AB blood, for example, your entire body is programmed to make A and B antigens on crimson blood cells. A man or woman with variety O blood isn’t going to deliver any antigens.  

Blood is mentioned to be “positive” or “detrimental” based on whether or not there are proteins on the pink blood cells. If your blood has proteins, you’re Rh positive


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Individuals with type O- blood are considered “universal donors” mainly because their blood isn’t going to have any antigens or proteins, this means anybody’s system will be ready to take it in an emergency.

But why are there unique blood styles? Researchers will not totally know, but elements these as the place someone’s ancestors are from and previous bacterial infections which spurred protective mutations in the blood could have contributed to the diversity, in accordance to Dr. Douglas Guggenheim, a hematologist with Penn Medication. Persons with kind O blood may well get sicker with cholera, for illustration, when individuals with kind A or B blood might be far more very likely to experience blood clotting concerns. Although our blood cannot preserve up with the diverse organic or viral threats heading all around in real time, it might mirror what’s transpired in the earlier.

“In quick, it can be nearly like the physique has advanced all over its environment in get to guard it as finest as probable,” Guggenheim suggests.

The blood types most at-possibility for heart disease 


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People today with sort A, form B or type AB blood are a lot more likely than people with style O to have a coronary heart assault or encounter heart failure, according to the American Coronary heart Affiliation. 

Though the amplified danger is smaller (types A or B experienced a combined 8% greater danger of coronary heart assault and 10% greater danger of coronary heart failure, according to one particular massive research) the distinction in blood clotting rates is substantially higher, for every the AHA. Persons in the exact research with variety A and B blood were being 51% more probably to build deep vein thrombosis and 47% additional possible to develop a pulmonary embolism, which are severe blood clotting disorders which can also boost the possibility of coronary heart failure.

A explanation for this increased chance, according to Guggenheim, could have to do with inflammation that takes place in the bodies of persons with form A, variety B or type AB blood. The proteins existing in type A and variety B blood may well bring about more “blockage” or “thickening” in the veins and arteries, major to an greater chance of clotting and coronary heart disorder. 

Guggenheim also thinks this may explain the anecdotal (but inconclusive) lessen in hazard of severe COVID-19 ailment in persons with style O blood, which has influenced exploration. Intense COVID-19 sickness usually results in coronary heart troubles, blood clotting and other cardiovascular challenges.


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Other effects of blood sort

People with kind O blood love a somewhat lessen threat of heart condition and blood clotting, but they might be much more inclined to hemorrhaging or bleeding diseases. This might be primarily legitimate right after childbirth, in accordance to a research on postpartum blood decline, which found an amplified chance in gals with sort O blood.

Folks with variety O blood may also fare even worse right after a traumatic injury thanks to increased blood decline, according to a research published in Critical Treatment.

Other exploration has uncovered an amplified threat for cognitive impairment in men and women with kind AB blood when when compared to folks with variety O. Cognitive impairment consists of things like problems remembering, focusing or producing conclusions. 

Should really I adjust my life style primarily based on my blood style? 

Although investigation readily available now shows that blood kind can idea the scale in terms of someone’s threat of establishing heart disorder, significant aspects such as food plan, exercise or even the degree of air pollution you might be exposed to in your local community are also big gamers in deciding heart well being. 

Guggenheim says that for clients attempting to retain their heart healthier, you can find no particular advice that he’d make other than a excellent coronary heart nutritious food plan that lowers swelling, no matter of someone’s blood kind. 


Lean proteins, healthful fats, fruits, veggies and total grains are all component of a heart-wholesome food plan.

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But, he notes, potential research could provide additional definitive ways medical doctors take care of people centered on their blood style. All variables deemed equally, a patient with wholesome cholesterol ranges and variety A blood may well reward from taking aspirin every single working day whereas it may well not be important for a human being in the same boat with variety O blood. 

“A nicely-balanced, coronary heart-balanced diet in general is going to be what any medical professional is likely to suggest, and I would say that ABO does not improve that,” Guggenheim states. 

“I will not feel there’s a protective advantage from just obtaining form O blood that contributes to currently being scot cost-free,” he adds.

The info contained in this article is for academic and informational reasons only and is not supposed as wellness or clinical tips. Usually talk to a medical doctor or other qualified overall health company with regards to any issues you may possibly have about a health-related situation or overall health goals.