Trump falsely dismisses virus danger: ‘You catch it, you get better, and you’re immune’

The president’s continued effort to minimize the danger comes as more than 211,000 American lives have died from the virus that continues to spread in many parts of the U.S., including inside the White House and within the ranks of his own administration.

PHOTO: President Donald Trump pulls off his protective face mask as he poses atop the Truman Balcony of the White House after returning from being hospitalized at Walter Reed Medical Center for coronavirus disease (COVID-19) treatment, Oct. 5, 2020.

President Donald Trump pulls off his protective face mask as he poses atop the Truman Balcony of the White House after returning from being hospitalized at Walter Reed Medical Center for coronavirus disease (COVID-19) treatment, Oct. 5, 2020.

President Donald Trump pulls off his protective face mask as he poses atop the Truman Balcony of the White House after returning from being hospitalized at Walter Reed Medical Center for coronavirus disease (COVID-19) treatment, Oct. 5, 2020.

Even as he touted the Regeneron antibody treatment he’s taken as a “cure,” without evidence, he portrayed his hospitalization as having been unnecessary and suggested he could have “would have done it fine without drugs.”

“I didn’t have to go in frankly, I think it would have gone away by itself,” Trump said.

The president’s confidence in his condition comes after he was twice administered oxygen in recent days as he has fought the virus and seemed to confirm he is still being treated with a steroid, even as he said he is off all other medications.

“I think I’m taking almost nothing,” Trump said. “I think you go a little bit longer on, they have steroid, it’s not heavy steroid, they have that go a little bit longer, but I am not taking, I am almost not taking anything. I feel great.”

The White House and the president’s doctors have refused to answer basic questions about Trump’s illness and treatments, such as when he last tested negative for COVID-19 before he received a positive test and what impact the virus has had on his lungs.

“I will be tested very soon, but I am essentially very clean, they say it’s over a period of six, seven days, and I was — you know amazing thing happened to me I just went in, I didn’t feel good. And that’s OK, I expected that at some point,” Trump said, likening the virus to a “microscopic piece of dust.”

Despite not having been tested, the president said he doesn’t think he is contagious “at all anymore” and said he is feeling so well that he would like to do a rally tonight and felt he could have done one last night.

The president said whether or not he is contagious, if he were at a rally

Immune Cells Show the Way in This Medical Mystery

A 54-year-old man presents to a foot and ankle clinic in Maryland with a diffuse, hard lesion in the middle of the arch of his left foot; it is tender to the touch and painful to walk on.

He explains that it began developing gradually about 3 years earlier as a dry, scaly spot, and that the skin later cracked but there was no pain. He says he had not been concerned, since he had a history of having severe eczema and dry patches of skin in the same spot on his foot.

However, his efforts to treat the eczema with topical cortisone cream and “over-the-counter acid” have been ineffective, he said, adding that he became concerned when the lesion slowly grew thicker and harder.

The patient’s surgical and medical histories include thyroidectomy (for thyroid cancer) at age 28, a diagnosis of bipolar disorder, headaches/migraines, and high blood pressure. His family history is unremarkable, and clinical assessment reveals no major abnormalities.

Dermatological Examination

Dermatological assessment shows a 3.0-cm, scaly, keratotic patch with slight erythema in the plantar central region of the left arch, which is notably tender to palpation. There is no evidence of skin atrophy or lymphadenopathy. Laboratory test results are within normal limits.

Clinicians perform a skin punch biopsy and send the sample for histological evaluation.

The report notes infiltration of atypical lymphocytes in the upper dermis. Most of the atypical lymphocytes are round or ovoid with a cerebriform nuclear contour but with no clear nuclear membrane or nucleoli.

Single units or small clusters of these have infiltrated up into the epithelial layers (epidermotropism), down into the eccrine sweat glands (syringotropism) and the walls of the blood vessels in the dermis.

image

Histopathology and immunostaining profiles of mycosis fungoides palmaris et plantaris: (A) An infiltrate of the atypical lymphocytes in the upper dermis (hematoxylin and eosin [H&E], 40×1). (B) Round or ovoid atypical lymphocytes with cerebriform nuclear contour and no clear nuclear membrane or nucleoli (HE, 400×1). (C) Atypical lymphocytes infiltrating into the epidermis (epidermotropism) (HE, 100×1). (D) Atypical lymphocytes infiltrating into eccrine sweat glands (syringotropism) (HE, 100×1). (E) Perivascular infiltration of the atypical lymphocytes in the dermis (HE, 100×1). (F) Strong CD4 expression in atypical lymphocytes (3, 3 -diaminobenzidine [DAB], 100×1). (G) Reduced CD7 expression in atypical lymphocytes (DAB, 100×1). (H) Reduced CD8 expression in atypical lymphocytes (DAB, 100×1).

Immunostaining of the atypical lymphocytes shows almost uniformly strong positive staining for CD3, CD4 antibodies and about 30% positivity for CD7 and CD8; staining for CD20 was negative.

Clinicians note an approximately 3:1 ratio of CD4- to CD8-positive cells. Results of periodic acid-Schiff staining for fungal elements are negative for both spores and hyphae; yet the histomorphology and immunostaining profiles are judged to be consistent with mycosis fungoides palmaris et plantaris (MFPP).

The team discusses the treatment options with the patient, and he is referred to a dermatologist. The patient receives topical psoralen plus ultraviolet A (PUVA) photochemotherapy, which results in complete remission.

At 5-year follow-up, the

Elderly hit so hard by COVID-19 because of lower levels of certain immune cells

Elderly people who get COVID-19 have lower levels of important immune cells, which may explain why they are more likely than younger patients to have severe symptoms or die, new research suggests.

For the study, the researchers analyzed blood samples from 30 people with mild COVID-19, ranging in age from the mid-20s to late-90s. Compared with healthy people, all of the COVID-19 patients had lower numbers of T cells — which target virus-infected cells — in their blood.

But COVID-19 patients over 80 years of age had fewer T cells than those who were younger, and so-called “killer” T cells in older patients produced lower amounts of cytotoxic molecules that find and kill infected cells, the investigators found.

This age-related difference in immune response may partially explain why older COVID-19 patients have more severe illness, according to the authors of the study published this month in the journal mBio.

“Elderly people have more severe diseases compared to young people, and we found that the cytotoxic part of immune control is not as efficient to respond to the virus in older people,” said study leader Gennadiy Zelinskyy, a virologist at University Hospital Essen, in Germany.

The lower levels of T cells in COVID-19 patients is among the many unwelcome surprises of the pandemic, he noted in a news release from the American Society for Microbiology.

Once inside the body, most viruses trigger a boost in T cells, including cytotoxic-producing killer T cells that play a critical role in destroying virus-infected cells. If a person’s immune system produces fewer of these T cells, it has greater difficulty combating a viral infection.

The findings suggest that cytotoxic T cells play a key role in control of early infections, but Zelinskyy said it’s too soon to know if these cells can be used to create an immunotherapy against the new coronavirus.

More study is needed to understand the potential risks and benefits of interfering with T cells as a way to control the new coronavirus and other viruses, he concluded.

More information
The U.S. Centers for Disease Control and Prevention has more on COVID-19.

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Immune system holds clues to virus reaction

One of COVID-19’s scariest mysteries is why some people are mildly ill or have no symptoms and others rapidly die — and scientists are starting to unravel why.

An international team of researchers found that in some people with severe COVID-19, the body goes rogue and attacks one of its own key immune defenses instead of fighting the coronavirus. Most were men, helping to explain why the virus is hitting men harder than women.

And separate research suggests that children fare better than adults thanks to robust “first responder” immune cells that wane with age.


They’re the latest in a list of studies uncovering multiple features of the immune system’s intricate cascade that can tip the scales between a good or bad outcome. Next up: Figuring out if all these new clues might offer much-needed ways to intervene.

“We have the knowledge and capability of really boosting many aspects of the immune system. But we need to not use the sledge hammer,” cautioned Dr. Betsy Herold of New York’s Albert Einstein College of Medicine, who co-authored the child study.

Adding to the complexity, people’s wildly varying reactions also reflect other factors, such as how healthy they were to begin with and how much of the virus — the “dose” — they were exposed to.

“Infection and what happens after infection is a very dynamic thing,” said Alessandro Sette, a researcher at the La Jolla Institute for Immunology in San Diego, who is studying yet another piece of the immune response.

IMMUNE PRIMER

There are two main arms of the immune system. Innate immunity is the body’s first line of defense. As soon as the body detects a foreign intruder, key molecules, such as interferons and inflammation-causing cytokines, launch a wide-ranging attack.

Innate immune cells also alert the slower-acting “adaptive” arm of the immune system, the germ-specific sharpshooters, to gear up. B cells start producing virus-fighting antibodies, the proteins getting so much attention in the vaccine hunt.

But antibodies aren’t the whole story. Adaptive immunity’s many other ingredients include “killer” T cells that destroy virus-infected cells — and “memory” T and B cells that remember an infection so they spring into action quicker if they encounter that germ again.

A MISSING PIECE

Usually when a virus invades a cell, proteins called Type I interferons spring into action, defending the cell by interfering with viral growth. But new research shows those crucial molecules were essentially absent in a subset of people with severe COVID-19.

An international project uncovered two reasons. In blood from nearly 1,000 severe COVID-19 patients, researchers found 1 in 10 had what are called auto-antibodies — antibodies that mistakenly attack those needed virus fighters. Especially surprising, autoimmune disorders tend to be more common in women — but 95% of these COVID-19 patients were men.

The researchers didn’t find the damaging molecules in patients with mild or asymptomatic COVID-19.

In another 660 severely ill patients, the same team found 3.5% had gene mutations that didn’t produce Type I interferons.

Each

3 Ways To Strengthen Your Immune System And Keep COVID-19 At Bay

Your immune system defends you against microorganisms that cause all sorts of infections and diseases. But with the increased threat brought by the ongoing pandemic, your immune system could use an extra boost.

While bolstering your immunity is easier said than done, several dietary and lifestyle changes may strengthen your body’s natural defenses and help you fight harmful pathogens or disease-causing organisms. We’ve listed some of the simple things you can do daily to help boost your immune system. 

1. Get the right nutrients your body needs

Food Supplements Turmeric supplements can add a lot of what you need. Photo: revivesups.com

Food is your best source of everything. Fill half your plate with vegetables and fruit, and split the other half between lean protein and grains, as the USDA’s MyPlate guidelines recommend.

You should also take some time to think about what you’re getting out of your food. In this day and age of takeout and fast food, it can be hard to get all the nutrients you need. Food supplements, as the name suggests, can be a good way to supply the nutrients missing in your regular diet. Just remember to consult your nutritionist, dietician, or physiologist before taking supplements.

In addition, there are even dedicated supplements for men and women: there is evidence to suggest that men and women have different nutritional needs. For instance, men need a little more macronutrients than women while women need more calcium, iron, and folic acid intake than men.

2. Manage your stress

Stress management Manage your stress to boost your immune system. Photo: Pixabay

Everybody gets stressed. Short bursts of stress may help your immune system by inhibiting inflammation. But lasting stress is a problem. It can hamper your immune system.

Taming stress is something that anybody can attain. Making these steps part of your stress management plan can help you control your stress more:

  • Learn and use relaxation techniques.
  • Exercise.
  • Consider taking Cortisol reduction supplements.
  • Take time for yourself.
  • Build your support network of people you can talk to.
  • Consider counseling, especially when you’re going through a very stressful time.

Cortisol supplement Reduce cortisol to get more sleep Photo: revivesups.com

3. Get enough sleep

Get enough sleep Getting enough sleep can help improve your immune performance. Photo: Pixabay

Studies show that people who don’t get quality sleep or enough sleep are more likely to get sick after being exposed to a virus, such as a common cold. Lack of sleep can also affect how fast you recover if you do get sick.

During sleep, your immune system releases proteins called cytokines, some of which help promote sleep. Certain cytokines need to increase when you have an infection or inflammation, or when you’re under stress. Sleep deprivation may decrease the production of these protective cytokines. In addition, infection-fighting antibodies and cells are reduced during periods when you don’t get enough sleep. Cortisol reduction supplements by Revive Sups can help calm you down by reducing the amount of cortisol your body produces. Cortisol is responsible for raising your