It’s Tough to Change the Minds of ‘Vaccine-Hesitant’ Parents, Study Finds | Health News

By Amy Norton
HealthDay Reporter

(HealthDay)

WEDNESDAY, Oct. 14, 2020 (HealthDay News) — When parents have concerns about the safety of childhood vaccinations, it can be tough to change their minds, as a new study shows.

The study involved “vaccine-hesitant” parents — a group distinct from the staunch “anti-vaxxer” crowd. They have worries about one or more routine vaccines, and question whether the benefits for their child are worthwhile.

Even though those parents are not “adamantly” opposed to vaccinations, it can still be hard for pediatricians to allay their concerns, said Jason Glanz, lead researcher on the study.

So Glanz and his colleagues looked at whether giving parents more information — online material “tailored” to their specific concerns — might help.

It didn’t. Parents who received the information were no more likely to have their babies up to date on vaccinations than other parents were, the study found.

The news was not all bad. Overall, more than 90% of babies in the study were all caught up on vaccinations.

So it may have been difficult to improve upon those numbers, according to Glanz, who is based at Kaiser Permanente Colorado’s Institute for Health Research in Aurora.

But, he said, it’s also possible the customized information reinforced some parents’ worries.

“It might have done more harm than good,” Glanz said.

That’s because among vaccine-hesitant parents, those who were directed to general information that was not tailored, had the highest vaccination rates — at 88%.

The findings were published online Oct. 12 in Pediatrics.

Childhood vaccination rates in the United States are generally high. But studies show that about 10% of parents either delay or refuse vaccinations for their kids — generally over safety worries.

Routine childhood vaccines have a long history of safe use, Glanz said, but some parents have questions. They may have heard that certain ingredients in vaccines are not safe, or worry that their baby is being given “too many” immunizations in a short time.

And during a busy pediatrician visit, Glanz said, it can be hard to address all those questions.

So his team tested a web-based tactic to augment routine checkups. They randomly assigned 824 pregnant women and new parents to one of three groups: One received standard vaccine information from their pediatrician; another was directed to the study website for additional, but general, information on immunizations; and the third received tailored information from the website.

That tailoring was done with the help of a survey that asked parents about their vaccine beliefs and concerns.

In the end, however, the targeted messaging flopped. It made no difference among parents overall: Across the three groups, between 91% and 93% of babies were up to date on vaccinations at 15 months of age.

And among the 98 parents who were deemed vaccine-hesitant, the tactic seemed to backfire: Only 67% of those babies were up to date compared to 88% of those whose parents received general vaccine information. The rate was 75% in the standard-care group.

Dr. Edgar Marcuse,

Trump’s use of Regeneron treatment creates ‘tough situation’: CEO

President Donald Trump’s use of Regeneron’s experimental coronavirus treatment creates “a very tough situation” for the drugmaker since it hasn’t been cleared for broader use, CEO Dr. Leonard Schleifer told CNBC on Monday.

The president, who announced Friday that he and first lady Melania Trump tested positive for the coronavirus, was given an 8 gram dose of Regeneron’s monoclonal antibody treatment, his doctors said.

The company said it provided the drug to the president in response to a “compassionate use” request from Trump’s doctors, which allows for expanded access to experimental drugs for “immediately life-threatening” illnesses, according to the Food and Drug Administration. It allows patients to access an investigational drug outside of clinical trials in lieu of adequate other treatments.

That means that while the president’s doctors were confident enough of the drug’s benefit to administer it to Trump, the treatment remains unavailable to most Americans.

“We have tried to take a principled approach until there is a broader authorization,” Schleifer told CNBC’s Meg Tirrell on “Squawk Box.” “Asking somebody like the president to go into a clinical trial just wasn’t practical.”

Until the FDA takes a look at all the available data on the benefits and risk of the drug for Covid-19 patients, patients who want to receive the treatment should enroll in a clinical trial, Schleifer said. He added that patients in clinical trials are closely monitored so that researchers can understand how the drug affects the disease, but at least a third of patients will receive a placebo.

“Giving it to [Trump] or to others who might not be able or don’t qualify for clinical trials is the right use of compassionate use. That’s for small numbers of people, for these exceptions,” he said. “We want everybody to be potentially able to benefit. We understand we don’t make that decision. This is a decision the FDA has to make.”

Schleifer added that he thinks the treatment meets “a lot of” the FDA’s standards for an emergency authorization. But he said the company needs to continue to collect data in controlled clinical trials to better understand the treatment. But as trials continue, the virus continues to infect more than 40,000 people every day across the U.S.

“This is all very complicated because it’s real lives at stake” he said. “If it’s my loved one or your loved one, … yes, we want to give this if we can help them. Of course, we want to get definitive evidence, so it’s a tough act to balance.”

Shares of the company were up more than 5% in early trading Monday.

Some analysts have speculated that the use of Regeneron’s antibody cocktail to treat the president is a tacit endorsement of the drug and could signal a swift approval by the FDA. Schleifer, however, tried to assure the public in the CNBC interview that the FDA has its own standards for authorization and the White House does not play a role. 

The class of drug has long been used to

Tough menopause may signal future heart issues, study says

As if the misery of hot flashes, night sweats and sleep troubles weren’t enough, now new research suggests that women who routinely experience moderate to severe menopausal symptoms have a higher risk of stroke and heart disease.

“This analysis assessed various menopausal symptoms and their association with health outcomes. Women with two or more moderate to severe menopausal symptoms had an increased risk of stroke and cardiovascular disease,” said study author Dr. Matthew Nudy, a cardiology fellow at Penn State Hershey Medical Center.

This study didn’t prove a cause-and-effect relationship, it only showed an association between menopausal symptoms and stroke and other heart and blood vessel diseases. It’s possible that menopause symptoms might not be a cause of these problems at all. It may be that other factors, such as obesity or diabetes, may lead to both menopausal symptoms and poor health outcomes.

Nudy also noted that past research has shown that women with menopausal symptoms often have other risk factors for heart disease and stroke, such as high blood pressure and cholesterol. They also may have poorer blood vessel health and increased levels of inflammation.

The latest research used data from a previous trial of more than 20,000 women between the ages of 50 and 79. The average follow-up time for the study was seven years.

The study looked for symptoms that included:

  • Hot flashes
  • Night sweats
  • Dizziness
  • Irregular heartbeats, such as a racing heartbeat or a feeling of skipped beats
  • Tremors
  • Feeling restless or fidgety
  • Feeling tired
  • Difficulty concentrating or forgetfulness
  • Mood swings
  • Vaginal dryness
  • Breast tenderness
  • Headache or migraine
  • Waking up multiple times at night.

The researchers found that when two or more of these symptoms were moderate to severe, the odds of stroke increased by 41%. The odds of any cardiovascular disease increased by 37% in women with two or more moderate to severe symptoms compared to women who had none.

Women who have multiple or more moderate to severe symptoms from menopause may be more likely to see a doctor for relief of those symptoms. Nudy said that’s a good opportunity for doctors to assess their heart disease and stroke risk.

Dr. Eugenia Gianos, director of women’s heart health at Lenox Hill Hospital in New York City, reviewed the study and said it reaffirms previous studies on potentially negative effects associated with menopausal symptoms.

“Many cardiac syndromes are unique to women and hormonal differences may explain the differences noted,” Gianos said.

“Unfortunately, supplementation with calcium and vitamin D did not improve outcomes,” she added.

Future research needs to determine what factors may be responsible for the negative effects of menopause and menopausal symptoms on women’s health, and find ways to ease menopausal symptoms and any poor outcomes linked to them, Gianos noted.

The findings were presented this week at the virtual meeting of the North American Menopause Society. Findings presented at meetings are typically viewed as preliminary until they’ve been published in a peer-reviewed journal.

More information

Learn more about menopausal symptoms from the U.S.

Tough Menopause May Signal Future Heart Woes | Health News

By Serena Gordon
HealthDay Reporter

(HealthDay)

THURSDAY, Oct. 1, 2020 (HealthDay News) — As if the misery of hot flashes, night sweats and sleep troubles weren’t enough, now new research suggests that women who routinely experience moderate to severe menopausal symptoms have a higher risk of stroke and heart disease.

“This analysis assessed various menopausal symptoms and their association with health outcomes. Women with two or more moderate to severe menopausal symptoms had an increased risk of stroke and cardiovascular disease,” said study author Dr. Matthew Nudy, a cardiology fellow at Penn State Hershey Medical Center.

This study didn’t prove a cause-and-effect relationship, it only showed an association between menopausal symptoms and stroke and other heart and blood vessel diseases. It’s possible that menopause symptoms might not be a cause of these problems at all. It may be that other factors, such as obesity or diabetes, may lead to both menopausal symptoms and poor health outcomes.

Nudy also noted that past research has shown that women with menopausal symptoms often have other risk factors for heart disease and stroke, such as high blood pressure and cholesterol. They also may have poorer blood vessel health and increased levels of inflammation.

The latest research used data from a previous trial of more than 20,000 women between the ages of 50 and 79. The average follow-up time for the study was seven years.

The study looked for symptoms that included:

  • Hot flashes
  • Night sweats
  • Dizziness
  • Irregular heartbeats, such as a racing heartbeat or a feeling of skipped beats
  • Tremors
  • Feeling restless or fidgety
  • Feeling tired
  • Difficulty concentrating or forgetfulness
  • Mood swings
  • Vaginal dryness
  • Breast tenderness
  • Headache or migraine
  • Waking up multiple times at night.

The researchers found that when two or more of these symptoms were moderate to severe, the odds of stroke increased by 41%. The odds of any cardiovascular disease increased by 37% in women with two or more moderate to severe symptoms compared to women who had none.

Women who have multiple or more moderate to severe symptoms from menopause may be more likely to see a doctor for relief of those symptoms. Nudy said that’s a good opportunity for doctors to assess their heart disease and stroke risk.

Dr. Eugenia Gianos, director of women’s heart health at Lenox Hill Hospital in New York City, reviewed the study and said it reaffirms previous studies on potentially negative effects associated with menopausal symptoms.

“Many cardiac syndromes are unique to women and hormonal differences may explain the differences noted,” Gianos said.

“Unfortunately, supplementation with calcium and vitamin D did not improve outcomes,” she added.

Future research needs to determine what factors may be responsible for the negative effects of menopause and menopausal symptoms on women’s health, and find ways to ease menopausal symptoms and any poor outcomes linked to them, Gianos noted.

The findings were presented this week at the virtual meeting of the North American Menopause Society. Findings presented at meetings are typically viewed as preliminary until they’ve been published in

Health Issues For Men That Can Make Sex Over 60 Tough

The healthcare discipline is the topic of a number of federal statutes, regulations, tips, interpretive data, and model guidance. Medicare does have to do a better job of curbing value will increase on account of pointless and typically harmful exams and medical procedures. On high of all of this, our healthcare systme isn’t falling apart. Germany, the primary country to implement nationwide healthcare, did so within the 1880’s, a long time earlier than America would see the intense growth of any kind of health insurance in any respect.

All of these nationwide healthcare techniques in different countries have their very own distinctive ways of undertaking the purpose of common healthcare. Doing so will keep you sated throughout the day so that you simply’re not ravenous at mealtime, which may trigger you to overeat or eat calorie-laden meals, and can maintain your metabolism humming.

A very important ingredient of healthcare administration is to grasp the key regulatory setting. While the remainder of the day may be spent caring for other people or being busy finishing every day duties, the bubble tub is time to care for you , and solely you.

The problem is the additional cost for those receiving FREE healthcare is handed onto those paying which includes the rich and poor. My father did not pay a cent for his healthcare because he was an illegal on the time. Additionally personal insurance carriers act in some nations in a complimentary method to cover such medical providers which aren’t covered beneath the governments’ plans, corresponding to cosmetic remedies.

I imagine many in the US don’t need universal healthcare due to what you talked about – they are benefiting from those profitable salaries, bonuses and insurance income. It will proceed to happen with or without common healthcare, unless the legislation changes to solely provide care to residents and legal residents.…